温小安1976年出生,研究员,博士生导师,主要从事抗代谢性疾病和抗肿瘤药物研究。2007年毕业于中国药科大学药物化学专业,获博士学位。2009年获第12届中国药学会-施维雅青年药物化学奖、全国优秀博士学位论文提名奖。2010-2012年获FFCSA(法中科学及应用基金会)资助,在法国里尔二大从事博士后研究。目前主持国家自然科学基金、江苏省自然科学基金等多项科研项目。

代表性论文:

1.  Xiaowei Sun, Xiaoan Wen (共一作),  Yan-yan Chen, Chen Shi, Chengzhe Gao, Yong Wu, Li-jun Wang, Xiu-hong Yang*,  Hongbin Sun*. Discovery of highly potent renin inhibitors potentially  interacting with the S3’ subsite of renin. European Journal of Medicinal  Chemistry 2015, 103, 269–288.

2.  Zeng-Wei Lai, Chunhong Li, Jun Liu, Lingyi Kong, Xiaoan Wen*,  Hongbin Sun*. Discovery of highly potent DPP-4 inhibitors by hybrid compound  design based on linagliptin and alogliptin. European Journal of Medicinal  Chemistry 2014, 83, 547–560.

3.  Jizhe Dong, Yanchun Gong, Jun Liu, Xiangfeng Chen, Xiaoan Wen*,  Hongbin Sun*. Synthesis and biological evaluation of all eight stereoisomers of  DPP-IV inhibitor saxagliptin. Bioorganic & Medicinal Chemistry  2014, 22, 1383–1393.

4.  Xiaowei Sun, Chengzhe Gao, Fan Zhang, Zhuang Song, Lingyi Kong,Xiaoan  Wen*, Hongbin Sun*. Electronic and steric effects on the intramolecular  Schmidt reaction of alkyl azides with secondary benzyl alcohols. Tetrahedron  2014,70, 643–649.

5.  Xiaoan Wen, Hongbin Sun*, Jun Liu, Keguang Cheng, Pu Zhang,  Liying Zhang, Jia Hao, Luyong Zhang, Peizhou Ni, Spyros E. Zographos, Demetres  D. Leonidas, Kyra-Melinda Alexacou, Thanasis Gimisis, Joseph M. Hayes, Nikos G.  Oikonomakos*. Naturally occurring pentacyclic triterpenes as inhibitors of  glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray  crystallographic studies. Journal of Medicinal Chemistry  2008, 51, 3540–3554.

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